Hairy Bacteria Walk and Talk

first_imgLittle hair-like projections on some bacteria, nearly invisible with light microscopes, are not just for decoration.  They do amazing things – as a pair of recent discoveries brought to light.  They help bacteria walk and talk.But can they dance?  Bacteria swim, but they also land on surfaces – and when they do, they put out little legs and walk.  This fascinating discovery, discussed on Science Daily, was made at UCLA.  The legs are called “type IV pili” in Pseudomonas, some of which cause diseases in humans.  “What enables this upright walking are appendages called type IV pili, which function as the analog of legs,” the article said.  “What’s more, walking allows P. aeruginosa to move with trajectories optimized for surface exploration, so that they can forage more effectively.”Social network:  Some bacteria are “wired” with their own electrical intranet.  This was announced also by Science Daily in an article titled, “Bacteria Grow Electrical Hair: Specialized Bacterial Filaments Shown to Conduct Electricity.”  Tiny microfilaments extend out between bacteria to provide a means of communication and mutual support – a kind of cellular FaceBook system.  These create large “living biological circuits” (see Live Science) made of “biological nanowires” that function just like social networks.  “This is the first measurement of electron transport along biological nanowires produced by bacteria,” a researcher said.    Science Daily explained, “A bacterial nanowire looks like a long hair sticking out of a microbe’s body.  Like human hair, it consists mostly of protein.”  Imagine if people communicated through their nanowires hair.  For bacteria, these networks are like a lifeline.  They exchange electrons, allowing bacteria to “breathe” and also communicate.    Microbes were already known to communicate with chemical signals.  The nanowire networks apparently provide a faster channel.  Said one of the researchers of the wired net, in stressful situations or when survival is at stake, “You want the telegraph, you don’t want smoke signals.”  One can only guess at what they are saying.  Do they speak in Morse code?  “The current hypothesis is that bacterial nanowires are in fact widespread in the microbial world,” he added.Humans tend to fear bacteria because of the few nasty kinds that cause disease, but many of these mechanisms at work in the microbial world may actually be beneficial.  That growing feeling extends to viruses, too.  Science Daily in another article spoke of a burgeoning field of “physical virology” that might allow doctors to employ viruses as “natural nanoparticles” for targeting therapeutic agents to cells, and another article in Science Daily discussed using “friendly bacteria” to treat bone cancer.  Could the germs we fear have had a function for good in the beginning?  Food for thought.  Answers in Genesis presented a lengthy article examining possible pathways how some beneficial E. coli and other bacteria might have degenerated into agents of disease.Darwin was obsessed with the appearance of natural evil in the world, because his acquaintance with natural theology did not take the Fall and the curse of sin seriously.  William Paley, for all his good reasoning, tried to use induction from the happy things in nature to a benevolent God.  Darwin saw design, but then looked at the suffering and disease everywhere.  Since he could not reconcile parasitism and disease with a benevolent God, he fell away from Paley’s view that originally was a strong influence in his thinking, and decided that design was just an illusion.  So he came up with an even more miracle-working god – chance!    Without understanding sin and judgment, one cannot correlate the irrefutable evidence of design with the existence of evil.  The world is like a bombed city, with relics of its original goodness clearly evident, but with the marks of judgment just as clear.  The Creator does not plan to make this world a better place.  He is going to destroy it and build a new one (II Peter 3:3-13).  In the meantime, He has left enough marks of good design to put individuals on trial without excuse for denying His existence (Romans 1:16-22), and yet in His grace has provided enough happiness to motivate all people to seek Him (Acts 14:8-18, Acts 17:22-30).  The gospel is a means to escape this present evil world destined for judgment, for a new creation in which righteousness dwells (II Peter 3:11-13).    Evolutionists mock at this, of course.  OK, take their answer: design is just an illusion.  Machinery emerges.  Weird stuff just happens sometimes (10/03/2010).  Evil doesn’t exist.  Everything came from nothing and is going nowhere.  Morality is a myth because it came from an undirected process of natural selection (10/10/2010).  Be consistent, now, and thank that E. coli when it lays you low, because it is merely showing it is more fit than you.  And no fair taking a stand on any moral issue, including the environment and climate change: the words ought and should are not in the Darwin Dictionary.  Take a random walk in Afghanistan; maybe the mutation-enhancing bullets will do you some good, whatever that word means.(Visited 59 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more

9 months agoJuventus captain Chiellini: We care about Supercoppa

first_imgAbout the authorCarlos VolcanoShare the loveHave your say Juventus captain Chiellini: We care about Supercoppaby Carlos Volcano9 months agoSend to a friendShare the loveJuventus captain Giorgio Chiellini says they’re determined to win the Supercoppa against Juventus tonight.Juve lost on penalties in the December 2016 Supercoppa in Doha.“We have changed a great deal in two years, but it is certainly a trophy we care about and want to win,” said Chiellini in his Press conference.“This appointment arrives mid-season, so it’s different to playing in August, but it remains an important competition and we’ve got to prove ourselves with actions rather than words, because we let a few too many of these trophies slip through our fingers in recent years and that is a shame.“We want to change that trend that has seen us lose the last two Supercoppa finals, and this is the ideal opportunity. It’s going to be a difficult match, but the objective is to start 2019 lifting a trophy above our heads.” last_img read more

LeBron James Destroyed Our Elo Ratings But Can He Beat The Warriors

197776ers*161551Trail Blazers162449✓ 1969Lakers*161458Celtics159842✓ YEARTEAMW-LPOINTS SCOREDPOINTS ALLOWEDSCORING MARGIN 1974Bucks*170980Celtics159220✓ 1954Nationals166661Lakers*160739✓ * Home-court advantage.Elo ratings are for each NBA Finals team as they entered the series. 1968Celtics*159456✓Lakers158644 YEAR▲▼FAVORITE▲▼ELO▲▼WIN PROB.▲▼WON▲▼UNDERDOG▲▼ELO▲▼WIN PROB.▲▼WON▲▼ 1987Lakers15-3120.6109.2+11.4 198276ers*169957Lakers168643✓ 1991Bulls*175067✓Lakers169733 1956Warriors*161775✓Pistons152925 1949Lakers*162584✓Capitols149016 2007Spurs*170570✓Cavaliers164130 2000Lakers*169968✓Pacers164332 1962Celtics*166980✓Lakers155720 2002Lakers*171780✓Nets160120 196776ers*174592%✓Warriors15418% 2004Lakers*169858Pistons168242✓ 2014Spurs*173076✓Heat163824 1996Bulls15-397.486.8+10.6 1984Celtics*170672✓Lakers163328 2005Spurs*171666✓Pistons167034 2015Warriors*180275✓Cavaliers171225 1963Celtics*167785✓Lakers153315 1971Bucks*170491✓Wizards15079 1986Celtics15-3114.4104.1+10.3 1997Bulls*179966✓Jazz175134 1989Pistons*176369✓Lakers170131 1986Celtics*180788✓Rockets164012 1961Celtics*166977✓Hawks157123 2001Lakers15-1103.490.6+12.8 1980Lakers*171262✓76ers168138 2001Lakers*176889✓76ers159211 1987Lakers*173872✓Celtics166128 1952Lakers*164667✓Knicks159433 1964Celtics*166970✓Warriors160230 198376ers*170771✓Lakers163829 2016Warriors*179070Cavaliers172530✓ 1959Celtics*164382✓Lakers151418 1955Nationals*163273✓Pistons155127 2008Lakers173759Celtics*168541✓ 1960Celtics*167678✓Hawks157522 1988Pistons169255Lakers*165845✓ The Cavaliers are great … but still a big underdog 1991Bulls15-2103.992.2+11.7 1951Royals*161574✓Knicks153126 1950Lakers172777✓76ers*159723 1985Lakers15-4126.3116.2+10.2 YEAR▲▼FAVORITE▲▼ELO▲▼WIN PROB.▲▼WON▲▼UNDERDOG▲▼ELO▲▼WIN PROB.▲▼WON▲▼ 1958Celtics*160365Hawks155935✓ There’s just one big problem for Cleveland: Golden State.Reason No. 3: Elo thinks the Warriors are insanely great — one of the two best teams ever, along with the 1995-96 Bulls.The Warriors’ current Elo rating is 1850. That’s the highest rating a team has held upon entering the NBA Finals. And it’s the second-highest rating a team has had at any point in the regular season or playoffs; the 1995-96 Chicago Bulls peaked at a rating of 1853 after sweeping the first three games of the finals.3The Bulls then lost Games 4 and 5 before recovering to win the title in Game 6, finishing with an Elo rating of 1823. It’s higher than the peak rating of last season’s 73-win Warriors, who topped out at 1839 after starting out the regular season 24-0.We’ll be publishing a deeper dive on the Warriors next week, but Elo’s affection for them isn’t hard to explain. They’re 27-1 over their last 28 games. That includes a 12-0 record in the playoffs and an average margin of victory of more than 16 points, which is the best playoff scoring margin of all time. And they’ve done all of this in the Western Conference, which is still a lot deeper than the East.4True, Golden State benefited from a playoff injury to the San Antonio Spurs’ Kawhi Leonard — although the Cavs were helped by injuries to the Toronto Raptors’ Kyle Lowry and the Celtics’ Isaiah Thomas. The Warriors are making it look so easy that they may even be underrated by the “eye test,” which tends to reward teams that triumph in the face of adversity. Other than in Game 1 of the Western Conference finals, the Warriors haven’t faced much adversity because they haven’t let their opponents get close. 1996Bulls*183284✓SuperSonics169516 1999Spurs*174580✓Knicks163120 1990Pistons*168860✓Trail Blazers166340 1981Celtics*166876✓Rockets157324 1985Lakers175260✓Celtics*169740 1978SuperSonics*161059Bullets159041✓ 1947Warriors*142352✓Stags143248 1998Jazz*176254Bulls176146✓ It’s become a rite of spring. Every year — or at least every year since LeBron James returned to the Cleveland Cavaliers — our NBA Elo ratings are skeptical of the Cavs when the playoffs begin. And every year, LeBron and Co. have smashed our poor algorithm to bits.In 2015, the Cavs entered the playoffs with a lukewarm 1631 Elo rating. That’s perfectly respectable, but the sort of rating you might associate with the Los Angeles Clippers or another 50-something-win team that you’d expect to lose in the second round or the conference finals. Instead, Cleveland reached the NBA Finals, losing to the Golden State Warriors in six competitive games even with a depleted roster.In 2016, the Cavs had a similarly good-but-not-great Elo rating — 1642 — when the playoffs began. But they blew through the Eastern Conference playoffs before beating the 73-win Warriors to win the NBA title, famously overcoming a 3-1 series deficit along the way. Their Elo rating finished at 1759, ranking them among the top 25 teams of all-time and implying that the system had massively underrated them initially.This year, Elo had the Cavs pegged lower still when the playoffs began last month. Although the Cavs were our preseason favorite to win the Eastern Conference, they slumped at the end of the regular season — losing 13 of their final 22 games, including their last four — and their Elo rating fell all the way to 1545. That isn’t good; it’s the sort of rating you’d normally associate with a No. 6 seed or some other team you’d expect to lose in the first or second round. Accordingly, the Cavs’ chances of winning the title drifted around in the low-to-mid single digits — variously at 2 percent to 5 percent according to our simulations — as the regular season wound down and the playoffs began.But the Cavs have gone 12-1 in the playoffs and won by an average score of 117-103. Their Elo rating has climbed by almost 150 points, to 1691. They clinched a return to the finals by beating the Boston Celtics by 33 points on Thursday. It’s been dominating stuff.So has Elo learned its lesson? Well, maybe not. Cleveland’s chances of winning the finals are just 10 percent according to the more advanced, “Carm-ELO” version of our ratings — and 13 percent according to the simpler, original Elo algorithm. Bookmakers also have the Cavs as underdogs, but not as heavily, implying that they have about a 30 percent chance to beat the Warriors again and repeat as champions.Giving Cleveland only a 10 percent chance is not the hill I want to die on. Our NBA projections are pretty simple, and sports betting markets are pretty sophisticated. While there are occasional exceptions, I’d usually defer to Vegas in the event of a major disagreement.1I wouldn’t say that of political betting markets, which aren’t as sophisticated and have a bad track record in recent years compared with simple polling averages. Still, we’ve gotten a lot of questions throughout the playoffs about why Elo hasn’t given the Cavs a better chance. There are basically three reasons — but the one that matters the most right now has nothing to do with the Cavs and everything to do with the Warriors.Reason No. 1: Elo doesn’t account for teams such as Cleveland finding a higher “gear” in the playoffs. We covered this point extensively before the playoffs began, so I won’t go into too much detail here. Our Elo projections — and most other projection systems — essentially treat regular-season basketball as equivalent to playoff basketball. But LeBron’s teams have a long history of performing at a much higher caliber in the playoffs than in the regular season.Maybe this is because James and his teammates conserve their energy; there aren’t a lot of high-leverage regular-season games in the Eastern Conference, as evidenced by the fact that the Cavs could play so crappily down the stretch run and still stumble into the No. 2 seed. Maybe it’s because LeBron is a terrific half-court player, and there’s a premium on the half-court game in the playoffs as defenses tighten up. In any event, the assumption that playoff basketball equals regular-season basketball seems to be pretty wrong in the case of the Cavs. This is something we plan on re-evaluating as we retune our NBA models this summer.Reason No. 2: Elo ratings heavily weight recent performance. That hurt Cleveland before, although it’s starting to help them now. Elo ratings were originally devised for chess, which doesn’t have any such thing as a “season.” Instead, performance continuously fluctuates up and down over time. Our Elo-based sports ratings mostly work the same way.2With some exceptions: Regular Elo ratings revert each team’s rating partway toward the league average at the start of each regular season. And the Carm-ELO version of our ratings start each team out with an initial rating each season based on our player projections. The more recent the game, the more heavily it gets weighted.I’d defend this as being the right assumption to make, in general. The degree to which Elo ratings fluctuate from game to game — which is governed by something called the K-factor — has been tested based on tens of thousands of NBA games. Other things held equal, a game played a week ago ought to tell you more than one played six months ago. Elo can be “smart” about catching cases like the 2014-15 Atlanta Hawks, who started out 40-8 but went 20-14 for the rest of the regular season before being swept by Cleveland in the conference finals.But for a team whose regular-season performance doesn’t tell you much about how they’re going to fare in the playoffs (like the Cavaliers), there isn’t much benefit to doubling down on recent play. Cleveland played pretty well in the first half of the regular season, but middlingly — sometimes even poorly — in the second half. Elo put a lot of emphasis on that late-season slump as the playoffs approached, and that made it more skeptical of the Cavs.Elo’s philosophy of rapidly adjusting its ratings is benefiting the Cavaliers now, however. Because of their dominance in the playoffs, the Cavs’ current Elo rating has rebounded. Their 1691 is the highest Elo rating they’ve had since Dec. 25, when they were at 1692 and had a 23-6 record after beating the Warriors.That’s a very good Elo rating. Since the ABA-NBA merger in the 1976-77 season, the average NBA Finals participant has entered the finals with a rating of 1695. So Elo is saying that despite their regular-season struggles, the Cavs are every bit as strong as the typical conference champion. 1994Rockets*166356✓Knicks165544 The Warriors have dominated the playoffs like no one before them 2010Lakers*168657✓Celtics167443 1966Celtics*165076✓Lakers155824 1973Lakers*166759Knicks164941✓ 1961Celtics8-2120.7109.1+11.6 1979SuperSonics162057✓Bullets*157743 1957Celtics*163075✓Hawks154125 1975Bullets*165975Warriors157125✓ 2012Thunder*173767Heat168633✓ 1948Warriors*149152Bullets150048✓ 2017Warriors*185087Cavaliers169113 1965Celtics*165375✓Lakers156525 1953Lakers*163251✓Knicks164149 1992Bulls*174264✓Trail Blazers170236 1971Bucks12-2109.194.6+14.5 PER GAME PLAYOFF AVERAGES 2003Spurs*174681✓Nets162419 1976Celtics*155857✓Suns154443 2009Lakers*176068✓Magic170332 2017Cavaliers12-1116.8103.2+13.6 1972Lakers*173890✓Knicks155510 1970Knicks*159566✓Lakers154934 2006Mavericks*171773Heat163727✓ Minimum 8 playoff games played.Source: Basketball-reference.com 1995Magic*162852Rockets163548✓ 2017Warriors12-0118.3102.0+16.3 2013Heat*175565✓Spurs171135 2011Heat*172155Mavericks171745✓ 1993Bulls174173✓Suns*163427 To put this in perspective, suppose you took an indisputably great team like the 1986-87 Los Angeles Lakers, who went 65-17 in the regular season and entered the NBA Finals with an Elo rating of 1738. Elo would have given the Lakers only a 20 percent chance to win a seven-game series over the Warriors, assuming that the Warriors had home-court advantage (as they will against the Cavs). Compared with that, the Cavaliers’ 10 percent or 13 percent chance doesn’t seem so bad. Still, I’d put a few dimes down on LeBron at Elo’s odds.CORRECTION (May 30, 4:05 p.m.): An earlier version of a table in this story gave an incorrect winner for the 1951 NBA Finals. It was the Rochester Royals, not the New York Knicks. read more

Football Zach Smith speaks out for first time since termination

OSU coaches Tony Alford (left) and Zach Smith stand together before the Buckeyes game against Rutgers on Oct. 1. Credit: Alexa Mavrogianis | Photo EditorWhile appearing on Columbus area radio station 105.7 The Zone, former Ohio State wide receiver coach and recruiting coordinator Zach Smith said athletic director Gene Smith knew about the domestic abuse allegations made against him in 2015. Zach Smith said he found out about the allegation from October 2015 from Gene Smith. He was told, “to be on the next flight home” when he was on the road recruiting by Ohio State’s athletic director. Zach Smith said in the interview that Gene Smith found out about the allegations because he believes “the Powell Police Department contacted Ohio State” and not Urban Meyer specifically. He also said many people knew about the allegations that were brought to the police department and that Meyer’s statement during Big Ten Media Days was a reaction to the allegation that he was arrested in 2015, which he said never happened.  On ESPN, Zach Smith said that if Meyer lost his job because of these allegations, “it would be dead wrong” and that he doesn’t know “what else Urban Meyer could have done.”Breaking silence for the first time since he was fired from Ohio State on July 23, Zach Smith said he never committed domestic abuse against his ex-wife Courtney Smith, calling the relationship “volatile” and “toxic.” In the interview with 105.7 The Zone, he said there were times where he would have to restrain her or “defensively move out of the situation.” Zach Smith also said there were times he would have to sleep at Ohio State’s football offices.Zach Smith said he does not think the situation involving him and his ex-wife Courtney should have led to him being fired from his position with the team. “I don’t think it was warranted,” Smith said in the radio interview. “The problem was it was going to be unfair for the players, the fans, the whole university, to go through the media uproar.”He said he still believes that nothing he did was illegal and, “it was behind closed doors between a husband and wife.” Meyer released a statement on Twitter saying that he knew about the 2015 allegations involving Zach Smith and that he took appropriate action at the time.When Zach Smith read Meyer’s statement on ESPN, he said “that’s who he is right there, it was just, accurate.”This story was updated at 6:33 p.m. to include quotes from Zach Smith’s ESPN interview. read more

Paul Pogba confirms rift with Jose Mourinho

first_imgFrance midfielder Paul Pogba has accepted he had some “small issues” with his boss at Manchester United, Jose Mourinho during this past season, however, he believes things have improved since his return to England.Speaking at a news conference at France’s World Cup training base in Moscow, Pogba said his second year with United was not ideal, according to ESPN.“It was a better season that the previous one,” Pogba said.“It was an experience. There were some small issues with [Mourinho], but they were nothing in the end.“Being a substitute, that sort of thing, it helps you to grow. I have to accept it.”harry maguire, manchester UnitedMaguire says United need to build on today’s win George Patchias – September 14, 2019 Harry Maguire wants his United teammates to build on the victory over Leicester City.During the summer, Harry Maguire was referred to as the ultimate…Pogba also defended international teammate Antoine Griezmann, who is struggling for form through two World Cup games despite scoring a penalty in the 2-1 victory over Australia.“Antoine is doing very, very well — he is happy,” Pogba said.“Just because he did not score in the second match [against Peru], it does not mean that it is not the same Grizou.“Leave my Grizou alone! You have forgotten about Euro 2016. Think about all of the defensive work he did against Peru. He helped us to keep them out.”last_img read more

Pep Guardiola admits fitness concerns

first_imgPep Guardiola says Manchester City’s players are still struggling for fitness ahead of their third Premier League game against Wolves.Guardiola has admitted the club are feeling the effects of a shortened pre-season due to the World Cup in Russia.Kevin De Bruyne and Goalkeeper Claudio Bravo are currently facing lengthy spells on the sidelines.However, the Spaniard is not fazed by the current injury problems and warned there is no chance of complacency creeping in.“The problem is that now – while we are not far away – we are still not fit,” said Guardiola.“We see how much the players spend for regeneration after the game. Normally it’s quicker – one or two days – now they need more time.Premier LeaguePremier League Betting: Match-day 5 Stuart Heath – September 14, 2019 Going into the Premier League’s match-day five with a gap already beginning to form at the top of the league. We will take a…“It’s because we didn’t make a pre-season. When we arrive, immediately after three-four days we played the Community Shield and Arsenal.“Some players need much more time to win power, strength. The players complain about muscular problems – that’s why Claudio got out, Kevin. This week Fernandinho had problems with regeneration after the game.“But it’s normal, we demand a lot, and still we are not in the best condition. Hopefully, after the international break, the team can be better and better.”Newly-promoted Wolves were the first team to stop City scoring in open play when they faced each other last October, and Guardiola admits the Midlands club “destroyed the Championship.”The Spaniard equally confirmed the club would not be seeking a free transfer replacement for Bravo and that Aro Muric will be second-choice goalkeeper behind Ederson after being recalled from a loan at NAC Breda.last_img read more

Sarri rues poor VAR decision in Blues defeat

first_imgMaurizio Sarri rued his team’s 1-0 loss to Tottenham in the Carabao Cup semi-final first leg suggesting Harry Kane was clearly offside in contrast to the VAR’s decision.After Kane was brought down by Chelsea goalkeeper Kepa Arrizabalaga inside the area, an initial offside decision was overturned by VAR as replays seemed to show Kane onside.However, Chelsea’s own footage seemingly shows Kane was slightly offside prompting Sarri to declare that the officials need to study the system better.💻 SARRI’S DIFFERENT ANGLE 💻Was Kane offside or not?Chelsea boss Maurizio Sarri says VAR got it wrong – and believes he has the different angle to prove it: https://t.co/13XGY1YSaN pic.twitter.com/57ooBiTE5CSacchi explains Sarri, Conte, and Ancelotti Manuel R. Medina – September 14, 2019 Arrigo Sacchi talked about how Sarri has a tougher time at Juventus than Conte at Inter; while Ancelotti’s “blood is boiling” at Napoli.Arrigo Sacchi…— Sky Sports Football (@SkyFootball) January 8, 2019Chelsea’s head coach said via Sky: “I saw the video from our camera a few minutes ago, it was offside. Our camera was in line with Kane, and it was offside, but it’s not important.“With the head, it’s offside. But it’s not important. It was important that the linesman stopped the run, he didn’t follow the ball, so he had a big influence on our defenders, and at the moment I think the English referees aren’t able to use the system.”He then said in his post-match press conference: “In Italy there is VAR, in the first period it was a disaster, difficult for the referee to use the system. At the moment here the refs are not ready to use it in the right way. Kane was offside, clearly offside, but it is not important.“They need to study better the system. It is very strange in the Premier League there is not this system and then in Carabao Cup there is.”last_img read more

Local Police Notice Influx Of Failure To Appear Arrests Following New Legislation

first_imgSgt. Cushman: “We find people who have a warrant and when we go to contact them they are sometimes in the act of committing another crime.” According to Sergeant Paul Cushman with KPD they noticed an influx of ‘failure to appear’ arrests since the first of the year: “We have seen an increase in our warrant arrests, many of those related to failure to appear for their court dates. We don’t have statistical information to say that it’s directly related to any new legislation, but they have seemed to coincide timing wise.” On February 17, KPD reported four separate arrests where they were dispatched to a crime in progress and ultimately arrested individuals at the scene with outstanding warrants. Sgt. Cushman: “Certainly there are a lot more people being released without a bail, and are essentially just given a court date, and are released after being arrested. So, rather than being held in jail until their court date they are being released, and then obviously not showing up “failing to appear” and so warrants are issued for their arrests.” The purpose of the program is to use a data-based, validated risk assessment took to make a recommendation to the court on conditions of release. The recommendation is based on two factors: the likelihood that the defendant will attend their court hearings and the likelihood that they defendant will engage in new criminal activity if released. But, ultimately, the decision is up to the judge.last_img read more